Axis Bio offers a range of syngeneic models to test your novel immunotherapeutic agents; many of these have been validated against checkpoint inhibitors. These models can be run as subcutaneous or orthotopic models and we have in-house FACS and IHC capabilities to back-up any efficacy data.

Cancer Type

Cell lines

FACS Panel Validated

Breast

4T1, EMT-6, TS/A

Colon

CT26, MC38, Colon26

Leukaemia

L1210

X

Lung

Lewis Lung

Lymphoma

A20, E.G7-OVA, EL4

X

Melanoma

B16F10, B16F1 CloudmanS91

Prostate

TRAMP-C2, RM-1

X

Renal

RENCA

 

Contact us today for more details on these cell lines and expert advice on experimental models utilising them.