Axis Bio offers a functional assay toolset that can be used to inform go/no go decisions for your oncology project. In addition, knowing the mechanism of action of your compound can guide the optimal design for further in vivo studies. These functional assays include:
In vitro drug combination studies
Clonogenic Assays
Target Validation studies
Adhesion, migration and invasion assays
Apoptosis Studies
Cell Cycle Analysis
Below are a list of cancer cell lines currently available for in vitro testing. If your cell line of interest is not on this list please contact us.
Cancer Type |
Cell line |
Bladder |
647-V, J82, RT112, RT4, UMUC-6, VM-CUB2 |
Brain |
KELLY, U118-MG, U87-MG, U251-MG |
Breast |
BT20, BT474, HCC38, JIMT-1, KPL-4, MDA-MB-157, MDA-MB-231, MDA-MB-436, MDA-MB-468, MCF-7, SKBR3, T47D, ZR-75-1 |
Bone |
Saos-2, U-2-OS |
Cervical |
HeLa |
Colorectal |
DLD-1, SW48, HT29, HCT116, SW620, LoVo, SNU-1411 |
Fibrosarcoma |
HT1080 |
Gastric |
NCI-N87 |
Hepatic |
HepG2 |
Leukaemia |
CCRF-HSB2, HL-60, Jurkat, K562, L363, NOMO-1, THP-1 |
Lung (NSCLC) |
A427, A549, H2122, H460, PC9 |
Lung (SCLC) |
DMS79, NCI-H510A, NCI-H69 |
Lymphoma |
FARAGE, Ramos, TMD8, Z138 |
Melanoma |
A375, G361, MeWo, SK-MEL-5 |
Myeloma |
MM.1S, RPMI8226 |
Ovarian |
A2780, HEY, HEY-T30, IGROV-1, OAW28, OVCAR3, SKOV3, TOV-112D |
Pancreatic |
AsPC-1, BxPC3, Capan-1, HPAFII, Hs766T, MAI Paca-1, PANC-1 |
Prostate |
LNCaP, DU145, PC3, 22rv1, VCaP |
Renal |
A498, 786-0, ACHN |